Simulations Reveal Key Role of Arg15 for Promiscuous Activity in HisA Enzyme

Org. Biomol. Chem., 2021, Accepted Manuscript DOI: 10.1039/D1OB02029C, PaperKshatresh Dutta Dubey, Warispreet Singh The HisA enzyme catalyzes the first step of histidine biosynthesis via Amadori rearrangement of substrate ProFAR. Since it possesses the most conserved and ancient TIM-barrel fold, it provides an ideal... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research