Evaluation of long-term respiratory problems in children with esophageal atresia

Aim: Esophageal atresia (EA) is the most common congenital anomaly of esophagus and associated with childhood respiratory morbidities. We aimed to evaluate the long-term respiratory problems of children with EA.Methods: Thirty-three children with EA were classified as patient group, 20 children with gastroesophageal-reflux-disease were classified as control group. Demographical findings, and clinical features as recurrent/chronic cough, recurrent pneumonia, history of hospitalization due to respiratory problems, history of aspiration pneumonia, diagnosis of asthma, presence of tracheomalacia were recorded. Results of spirometry, total IgE, eosinophil percentage were recorded.Results: In the patient group with median age of 6.7 years, 84.8% of them had recurrent or chronic cough, 51.5% had wheezing, 63.6% had a history of respiratory distress episode in the past year, 24.2% had recurrent pneumonia, 63.6% had history of hospitalization due to respiratory problems, 27.2% had history of aspiration pneumonia, 33.3% had asthma diagnosis, and 18.1% had tracheomalacia. Aspiration pneumonia and hospitalization were more frequent in the patient group (p=0.045, p=0.013,respectively). Respiratory function tests (FVC, FEV1, FEF25-75) were found significantly lower in the patient group (p
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring airway disease Source Type: research

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