HPV RNA and DNA testing in Polish women screened for cervical cancer - a single oncological center study

The Human papillomavirus (HPV) is a tiny double-stranded DNA virus (1). There are over 100 different forms of HPV, with 40 of them affecting the genital tract (2). Based on their epidemiological relationship with cervical cancer, sexually transmitted HPV is divided into two categories: low-risk (LR) and high-risk (HR) (3). The HR HPV encodes viral oncogenes known as E6 and E7, which are necessary to initiate and maintain epithelial cell neoplasia (4). Chronic infection with HR HPV is the main cause of cervical cancer, the fourth leading cause of cancer death in women worldwide (5).

Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - November 25, 2021 Category: OBGYN Authors: Marek G. Bebyn, Paulina Śledzińska, Joanna Wojtysiak, Wojciech Jóźwicki, Tomasz Mierzwa, Józef Dziedzic, Janusz Kowalewski, Marzena Anna Lewandowska Tags: Full length article Source Type: research