Transcatheter treatment for tricuspid valve disease
EuroIntervention. 2021 Nov 19;17(10):791-808. doi: 10.4244/EIJ-D-21-00695.ABSTRACTApproximately 4% of subjects aged 75 years or more have clinically relevant tricuspid regurgitation (TR). Primary TR results from anatomical abnormality of the tricuspid valve apparatus and is observed in only 8-10% of the patients with tricuspid valve disease. Secondary TR is more common and arises as a result of annular dilation caused by right ventricular enlargement and dysfunction as a consequence of pulmonary hypertension, often caused by left-sided heart disease or atrial fibrillation. Irrespective of its aetiology, TR leads to volume overload and increased wall stress, both of which negatively contribute to detrimental remodelling and worsening TR. This vicious circle translates into impaired survival and increased heart failure symptoms in patients with and without reduced left ventricular ejection fraction. Interventions to correct TR are underutilised in daily clinical practice owing to increased surgical risk and late patient presentation. The recently introduced transcatheter tricuspid valve interventions aim to address this unmet need. Dedicated expertise and an interdisciplinary Heart Team evaluation are essential to integrate these new techniques successfully and select patients. The present article proposes a standardised approach to evaluate patients with TR who may be candidates for transcatheter interventions. In addition, a state-of-the-art review of the available transcathe...
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Authors: Fabien Praz Denisa Muraru Felix Kreidel Philipp Lurz Rebecca T Hahn Victoria Delgado Michele Senni Ralph Stephan von Bardeleben Georg Nickenig J örg Hausleiter Antonio Mangieri Jose L Zamorano Bernard D Prendergast Francesco Maisano Source Type: research
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