Dithiocarbamation of spiro-aziridine oxindoles: a facile access to C3-functionalised 3-thiooxindoles as apoptosis inducing agents

Org. Biomol. Chem., 2021, Accepted Manuscript DOI: 10.1039/D1OB02102H, PaperShankaraiah Nagula, Akash P Sakla, Biswajit Panda, Kritika Laxmikeshav, Jay Prakash Soni, Sonal Bhandari, Chandraiah Godugu Herein, we report the first dithiocarbamation of spiro-aziridine oxindoles involving regiospecific ring-opening by in situ generated nucleophilic dithiocarbamates as an instant source of sulfur. This approach afforded C3-functionalised-3-thiooxindoles in good... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research