Development and external validation of a prediction model for tube feeding dependency for at least four weeks during chemoradiotherapy for head and neck cancer

Patients who receive chemoradiotherapy or bioradiotherapy (CRT/BRT) for locally advanced head and neck squamous cell carcinoma (LAHNSCC) often experience high toxicity rates interfering with oral intake, causing tube feeding (TF) dependency. International guidelines recommend gastrostomy insertion when the expected use of TF exceeds 4 weeks. We aimed to develop and externally validate a prediction model to identify patients who need TF ≥4 weeks and would benefit from prophylactic gastrostomy insertion.

Source: Clinical Nutrition - November 24, 2021 Category: Nutrition Authors: Anna C.H. Willemsen, Annemieke Kok, Laura W.J. Baijens, Jan Paul de Boer, Remco de Bree, Lot A. Devriese, Chantal M.L. Driessen, Carla M.L. van Herpen, Frank J.P. Hoebers, Johannes H.A.M. Kaanders, Rebecca T. Karsten, Sander M.J. van Kuijk, Roy I. Lalisan Tags: Original article Source Type: research