The chemistry of ferrocenesulfonyl fluoride revealed

Dalton Trans., 2021,50,16483-16487 DOI: 10.1039/D1DT03492H, CommunicationWilliam Erb, Thierry Roisnel The first general syntheses of polysubstituted ferrocenesulfonyl fluorides are described. Combining multigram-scale synthesis of ferrocenesulfonyl fluoride with orthogonal reactivity of sulfonyl fluoride led to a diversity of original derivatives. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research

Related Links:

This study provides pilot data for the further development ofL. casei exoproducts as an anti-inflammatory or anti-proliferative agent for the treatment of inflammatory and cancer diseases in gut. However, more data is needed before final conclusions ofL. casei cell-free supernatant ’s efficacy can be drawn.
Source: Inflammation - Category: Allergy & Immunology Source Type: research
This study was intended to explore the underlying mechanism by which ulinastatin (UTI) influenced the inflammation and apoptosis of renal tubular epithelial cells, HK-2.The effects of UTI on the cell viability of HK-2 cells were first measured by MTT and lactate dehydrogenase (LDH) detection kit. The apoptosis and inflammation of HK-2 cells were then determined by TUNEL, western blot, ELISA, and RT-qPCR. Then, the proteins in the Toll-like receptor 4 (TLR4)/nuclear factor κB (NF-κB) and nuclear factor erythroid 2–related factor 2 (Nrf2)/Heme oxygenase 1 (HO-1) signaling pathways were measured by western b...
Source: Inflammation - Category: Allergy & Immunology Source Type: research
AbstractIn 2019, a new disease characterized by yellow mottling on leaves was observed onMetaplexis japonica (Thunb.) Makino plants in Liaoning, China. Using RNA sequencing and PCR with overlapping primers, the complete nucleotide sequence of the circular double-stranded DNA genome of a new virus similar to caulimoviruses in diseased samples was determined. The genome comprised 7733 base pairs and was predicted to encode six proteins. It had the closest relationship to a caulimovirus, strawberry vein banding virus, based on sequence comparisons and phylogenetic analysis. Species-level sequence divergences from caulimovirus...
Source: Archives of Virology - Category: Virology Source Type: research
AbstractBeauveria bassiana, an entomopathogenic fungus, is used for arthropod pest control worldwide. Here, we report the discovery and characterization of a novel double-stranded RNA (dsRNA) mycovirus, Beauveria bassiana chrysovirus 2 (BbCV-2), isolated from a ChineseB. bassiana strain. The genome sequence of the virus was determined by metagenomic sequencing, RT-PCR, and RACE cloning and was found to consist of four dsRNA segments that are 3441  bp, 2779 bp, 2925 bp, and 2688 bp long, respectively. Each dsRNA segment contains a single ORF. The ORF of dsRNA1 encodes a 1114-amino-acid (aa) protein (123....
Source: Archives of Virology - Category: Virology Source Type: research
AbstractProteus mirabilis is one of the most frequent causes of catheter-associated urinary tract infections (CAUTIs) owing to its capability to colonize and develop crystalline multidrug-resistant (MDR) biofilms. Here, we report the isolation and partial characterization of three novel bacteriophages, vB_PmiM-ES1a, vB_PmiM-ES1b, and vB_PmiM-ES1c, which were active against the planktonic form and biofilms of the MDRP. mirabilis strain ES01, isolated from CAUTIs in Egypt. The antibiotic susceptibility profile of theP. mirabilis isolates showed resistance to most of the antibiotics tested. The isolated phages were identified...
Source: Archives of Virology - Category: Virology Source Type: research
AbstractOlea europaea geminivirus (OEGV) from olive accessions in Italy was characterized recently. OEGV was also detected during routine high-throughput sequencing screening of olive (cv. Leccino) material, and its complete bipartite genome segments were sequenced and shown to be 100% identical to those of the isolate from Italy. Using two pairs of newly designed primers targeting the AV1 and BV1 genes, OEGV was detected in randomly sampled olive trees from the U.S. Department of Agriculture National Clonal Germplasm Repository (USDA-NCGR) (21.4% or 6/28), commercial and residential settings in California (47.6% or 10/21)...
Source: Archives of Virology - Category: Virology Source Type: research
AbstractAlphasatellites (familyAlphasatellitidae) are circular, single-stranded DNA molecules (~1 –1.4 kb) that encode a replication-associated protein and have commonly been associated with some members of the familiesGeminiviridae,Nanoviridae, andMetaxyviridae (recently established). Here, we provide a taxonomy update for the familyAlphasatellitidae following the International Committee on Taxonomy of Viruses (ICTV) Ratification Vote held in March 2021. The taxonomic update includes the establishment of the new subfamilyPetromoalphasatellitinae. This new subfamily includes three new genera as well as the genusBabus...
Source: Archives of Virology - Category: Virology Source Type: research
AbstractViruses cause a variety of diseases in humans and other organisms. The most important defense mechanism against viral infections is initiated when the viral genome is sensed by host proteins, and this results in interferon production and pro-inflammatory cytokine responses. The sensing of the viral genome or its replication intermediates within host cells is mediated by cytosolic proteins. For example, cGAS and IFI16 recognize non-self DNA, and RIG-I and MDA5 recognize non-self RNA. Once these sensors are activated, they trigger a cascade of reactions activating downstream molecules, which eventually results in the...
Source: Archives of Virology - Category: Virology Source Type: research
AbstractHere, we report the discovery and molecular characterization of a novel mitovirus isolated from tissues ofLagenaria siceraria, named"Lagenaria siceraria associated mitovirus 1" (LsaMV1). Next-generation sequencing and adapter-ligation-mediated amplification were used to obtain the full-length genome sequence of LsaMV1. The genome of LsaMV1 is 3,098 nucleotides (nt) long and contains an opening reading frame (ORF) encoding a putative RNA-dependent RNA polymerase (RdRP). Homology searches and phylogenetic analysis of the 855-aa RdRP suggested that LsaMV1 is a member of a new species in the familyMitoviridae...
Source: Archives of Virology - Category: Virology Source Type: research
AbstractThe complete genome sequence of a double-stranded RNA (dsRNA) mycovirus that was isolated fromAlternaria solani strain DT-10 causing potato foliar disease was determined. The virus, designated as"Alternaria solani chrysovirus 1" (AsCV1), has four dsRNA segments (dsRNA 1-4) with a length of 3600 bp, 3128 bp, 2996 bp, and 2714 bp, respectively. The RNA-dependent RNA polymerase (RdRp, 1084 amino acids [aa]), putative capsid protein (905 aa), alphachryso-P3 (835 aa), and alphachryso-P4 (729 aa) were encoded by dsRNA1, dsRNA2, dsRNA3, and dsRNA4, respectively, which had the highest sequence identity of 41.77%-...
Source: Archives of Virology - Category: Virology Source Type: research
More News: Chemistry | Fluoride