Altered Intestinal Permeability and Drug Repositioning in a Post-operative Ileus Guinea Pig Model

CONCLUSIONS: The alteration in intestinal permeability is one of the factors involved in the pathogenesis of POI. We repositioned 3 drugs (mosapride, glutamine, and ketotifen) as novel therapeutic agents for POI.PMID:34642285 | PMC:PMC8521477 | DOI:10.5056/jnm21018
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Authors: Source Type: research