What are the Main Differences Between MIS-C and Kawasaki Disease?

Discussion SARS-CoV-2 or COVID-19 was first observed in Wuhan China in late 2019. By March 2020 it had spread to become a world-wide pandemic and continues today despite vaccination and other public health measures. Early on people were worried that children would be the major age group affected, but the major groups were older individuals and those with underlying health problems. That is not to say that children are not affected as they were and could have severe disease. However as an overall group, they tend to get the virus and have less severe symptoms than adults. Severe disease is about 1% of pediatric cases compared to 10-20% for adults, and pediatric mortality is estimated at < 0.1% compared to 5-15% for adults. Common presentations of COVID-19 in children include: *Fever/chills *Cough *Diarrhea Fatigue Headache Myalgia Nausea/emesis *Pharyngitis Rhinorrhea Anosmia/aguesia * = very common symptoms especially for mild disease. In April 2020 there were warnings “…about cases of older school-aged children and adolescents presenting with fever, hypotension, severe abdominal pain and cardiac dysfunction….”These children had laboratory findings of cytokine storm….Almost all of these children no longer required intensive care after only a few days and completely recovered, although rare deaths [occurred]….” These children and adolescents had a new condition called multisystem inflammatory syndrome in children or MIS-C. MIS-C h...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news