PPAR α agonist relieves spinal cord injury in rats by activating Nrf2/HO-1 via the Raf-1/MEK/ERK pathway

CONCLUSION: PPARα agonist PEA can relieve SCI in rats by inhibiting inflammatory responses and oxidative stress, which may involve a mechanism associated with the activation of Nrf2/HO-1 via the Raf-1/MEK/ERK pathway.PMID:34799468 | DOI:10.18632/aging.203699

Source: Aging - November 20, 2021 Category: Biomedical Science Authors: Haocong Zhang Dulei Xiang Xinwei Liu Liangbi Xiang Source Type: research