Ceftriaxone with Metronidazole Versus Piperacillin/Tazobactam in the Management of Complicated Appendicitis in Children: Results from a Multicenter Pediatric NSQIP Analysis

Acute appendicitis is the most common abdominal pediatric surgical emergency in the United States, with approximately 80,000 cases diagnosed each year [1,2]. Appendicitis is also associated with the greatest relative burden of organ space infections (OSI) among all pediatric surgical conditions and ranks third in antibiotic treatment days for hospitalized children behind pneumonia and cystic fibrosis [3]. Approximately 30% of children present with complicated appendicitis, which is associated with relatively high OSI rates, prolonged length of stay, and increased hospital cost [4 –10].
Source: Journal of Pediatric Surgery - Category: Surgery Authors: Tags: Original Article Source Type: research