Metal-free synthesis of 1H-isochromenes via benzyl ether-assisted, electrophilic addition of diaryl acetylenes

Org. Biomol. Chem., 2021, Accepted Manuscript DOI: 10.1039/D1OB01941D, PaperTzu-Hsuan Kuan, Trimurtulu Kotipalli, Cheng-Chun Chen, Duen-Ren Hou Bromotrimethylsilane (TMSBr) promoted, intramolecular cyclization of (o-arylethynyl)benzyl ethers to form 1H-isochromenes at room temperature is reported. Further studies indicated that the stability of vinyl carbocations is crucial, similar to the... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research