Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units

World J Hepatol. 2021 Oct 27;13(10):1215-1233. doi: 10.4254/wjh.v13.i10.1215.ABSTRACTEmerging worldwide data have been suggesting that coronavirus disease 2019 (COVID-19) pandemic consequences are not limited to the respiratory and cardiovascular systems but encompass adverse gastrointestinal manifestations including acute liver injury as well. Severe cases of liver injury associated with higher fatality rates were observed in critically ill patients with COVID-19. Intensive care units (ICU) have been the center of disposition of severe cases of COVID-19. This review discusses the pathogenesis of acute liver injury in ICU patients with COVID-19, and analyzes its prevalence, consequences, possible drug-induced liver injury, and the impact of the pandemic on liver diseases and transplantation programs.PMID:34786163 | PMC:PMC8568568 | DOI:10.4254/wjh.v13.i10.1215
Source: World Journal of Hepatology - Category: Gastroenterology Authors: Source Type: research