The 07:32 from Pen Mill

Sitting on the 07.32 from Pen Mill going to a meeting in Bristol I marvel at the things people still do to earn a living and count myself lucky to work at home. I never endure the daily commute amongst people intent only on getting to work (and back again). On the infrequent occasions, I happen to find myself amongst them, it’s now treat not trial. I’m aware this line has benefits those stuck on the tube in London will never know. It is truly beautiful, and I watch my fellow travellers, wondering how many gaze like sheep or cows through the carriage window, rather than read or listen their way through the journey, shut off from the world around them on their phone or some other device. I look at the brilliant blue sky and imagine God painted it just for my pleasure. The day holds the promise of warmth on skin and bone, and even in the city spirits will raise at the sight of a lovely day. The sun is bright, and the few clouds remind me of the rain at the weekend, washing everything fresh again. The banks are still spring green, bright, and verdant with vigour and growth. The trees in their lacey dresses are primped and preened in their seasonal best. But in a few short weeks it will all fade, replaced with the dusty grey-green of late summer. Each stop along the route adds new members to the company forming in the carriage and we all sway and bump in unison to the rattle of the wheels over tracks. Over on the opposite table seat is a woman putting on her face and I...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Fiction friday fiction short story Source Type: news

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Sitting on the 07.32 from Pen Mill going to a meeting in Bristol I marvel at the things people still do to earn a living and count myself lucky to work at home. I never endure the daily commute amongst people intent only on getting to work (and back again). On the infrequent occasions, I happen to find myself amongst them, it’s now treat not trial. I’m aware this line has benefits those stuck on the tube in London will never know. It is truly beautiful, and I watch my fellow travellers, wondering how many gaze like sheep or cows through the carriage window, rather than read or listen their way through the journ...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Fiction friday fiction short story Source Type: news
Dr. Gerald Levey, who led the transformation of UCLA ’s hospitals and medical school into a world-class academic health system, died at home of Parkinson’s disease on June 25. He was 84. Levey served the campus as vice chancellor of medical sciences and dean of the David Geffen School of Medicine at UCLA from 1994 to 2010. During his tenure, Levey amassed an extraordinarily long list of achievements, crowned by the construction of the Ronald Reagan UCLA Medical Center and the sealing of a $200 million gift to the UCLA School of Medicine by entertainment executive David Geffen.  “It&rsq...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases. Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA dam...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Last weekend I watched the film Collateral Beauty with my husband Steve, aside from being awed by the concept of the film and it’s core message it really got me thinking about what we’ve witnessed this past 10 months. The film focuses around three abstractions, Love, Time, and Death. As the central character, Howard, explains right at the beginning of the film, we long for love, we wish we had more time and we fear death. I realised that since the beginning of 2020 I’ve been increasingly living in a world that focused on me and mine and I had forgotten about the world I had previously inhabited which was ...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Happiness beauty compassion Source Type: news
Last weekend I watched the film Collateral Beauty with my husband Steve, aside from being awed by the concept of the film and it’s core message it really got me thinking about what we’ve witnessed this past 10 months. The film focuses around three abstractions, Love, Time, and Death. As the central character, Howard, explains right at the beginning of the film, we long for love, we wish we had more time and we fear death. I realised that since the beginning of 2020 I’ve been increasingly living in a world that focused on me and mine and I had forgotten about the world I had previously inhabited which was ...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Happiness beauty compassion Source Type: news
In conclusion, metabolomics is a promising approach for the assessment of biological age and appears complementary to established epigenetic clocks. Sedentary Behavior Raises the Risk of Cancer Mortality https://www.fightaging.org/archives/2020/06/sedentary-behavior-raises-the-risk-of-cancer-mortality/ Living a sedentary lifestyle is known to be harmful to long term health, raising the risk of age-related disease and mortality. Researchers here show that a sedentary life specifically increases cancer mortality, and does so independently of other factors. This is one of many, many reasons to maintain a re...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
What exactly is psychosis? What happens in the brain of a person with schizophrenia who is hallucinating? Schizophrenic Rachel Star Withers shares her personal hallucinations and delusions and Dr. Joseph Goldberg, who specializes in researching what goes on in the brain when someone is experiencing psychosis, joins to break down how the brain functions during psychotic episodes. Host Rachel Star Withers, a diagnosed schizophrenic, and co-host Gabe Howard delve into these intense subjects in this episode of Inside Schizophrenia.  Highlights from “Psychosis in Schizophrenia” Episode [02:13]  Rachel, do...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior Disorders General Inside Schizophrenia Mental Health and Wellness Active psychosis Delusions Delusions Hallucinations Living with Schizoprenia Mental Disorder Mental Illness Psychology psychotic Psychotic Break Source Type: blogs
A behavioral brain fad called “dopamine fasting” (#dopaminefasting) has been floating around the internet for the past year. The idea is that by restricting most of your pleasurable daily activities — from social media, to watching videos, gaming, talking, or even eating — you can “reset” your brain. The idea also plays into people’s simplistic beliefs about how the brain works. Can you have conscious control over discrete dopamine levels in your brain? Let’s delve into the science behind one of your brain’s most important neurotransmitters, dopamine. During a “d...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior General Mental Health and Wellness Motivation and Inspiration Psychology Research dopamine fasting Neuroscience Neurotransmitter social media Technology unplug Source Type: blogs
Alessia Buso1†, Marina Comelli1†, Raffaella Picco1, Miriam Isola1, Benedetta Magnesa1, Rado Pišot2, Joern Rittweger3,4, Desy Salvadego1, Boštjan Šimunič2, Bruno Grassi1,5 and Irene Mavelli1,6* 1Department of Medicine, University of Udine, Udine, Italy 2Institute for Kinesiology Research, Science and Research Centre, Koper, Slovenia 3Department of Pediatrics and Adolescent Medicine, University of Cologne, Cologne, Germany 4Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany 5Institute of Bioimaging and Molecular Physiology, National Research Council...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
In this study, we found that TNF-α resulted in an impairment of autophagic flux in microglia. Concomitantly, an increase of M1 marker expression and reduction of M2 marker expression were observed in TNF-α challenged microglia. Upregulation of autophagy via serum deprivation or pharmacologic activators (rapamycin and resveratrol) promoted microglia polarization toward M2 phenotype, as evidenced by suppressed M1 and elevated M2 gene expression, while inhibition of autophagy with 3-MA or Atg5 siRNA consistently aggravated the M1 polarization induced by TNF-α. Moreover, Atg5 knockdown alone was suffic...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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