The expression and clinical significance of the tRNA aspartic acid methyltransferase 1 protein in gastric cancer

ConclusionTRDMT1 was highly expressed in GC cell  lines and tissues. TRDMT1 expression was independent predictor of the OS of GC patients. TRDMT1 knockdown reduced GC cell migration and invasion. All these results suggested that TRDMT1 has the potential to be used as a target for the diagnosis and treatment of GC.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research