Urinary CXCL10 specifically relates to HLA-DQ eplet mismatch load in kidney transplant recipients

CONCLUSIONS: uCXCL10 specifically relates to HLA-DQ eplet mismatch load. This relationship can partly explain the previously reported association between uCXCL10 excretion and graft inflammation. An adequate evaluation of any potential non-invasive biomarker, such as uCXCL10, must take into account the HLA molecular mismatch.PMID:34774739 | DOI:10.1016/j.trim.2021.101494

Source: Transplant Immunology - November 14, 2021 Category: Transplant Surgery Authors: David San Segundo Sandra A Guiral-Foz Adalberto Benito-Hern ández Andr é Renaldo Fernández Alvaro Arnau Rosal ía Valero Mar ía Angeles Ramos-Barrón Mar ía Teresa García-Unzueta Jos é María Gómez-Ortega Marcos L ópez-Hoyos Juan Carlos Ruiz Emil Source Type: research