Prior Exposure to Non-Steroidal Anti-inflammatory Drugs Reduces the Rate of Organ Failure and In-Hospital Mortality in Acute Pancreatitis. A Retrospective Cohort Study.

Acute pancreatitis remains a public health concern worldwide. In the US alone it accounts for>290,000 admissions annually with a cost of $2.5 billion 1. During severe acute pancreatitis, pro-inflammatory cytokines set in motion the systemic inflammatory response syndrome (SIRS) which is responsible for the development of organ failure in the early phases of the disease 2. Development of organ failure defined as the presence of acute kidney injury, cardiovascular failure or respiratory failure; either alone or in combination is the main factor driving the high mortality rate of severe cases 2, 3.

Source: The American Journal of Medicine - November 15, 2021 Category: General Medicine Authors: Antonio Mendoza Ladd, Darwin Conwell, Thomas E Burroughs, Munigala Satish Tags: Clinical Research Study Source Type: research