In vivo analysis of neuroinflammation in the late chronic phase after experimental stroke

Conclusions: We conclude that the combined approach of USPIO-MRI and [11C]PK11195-PET allows to observe post-stroke inflammatory processes in the living animal in an intraindividual and longitudinal fashion, predicting long-term tissue fate. The non-invasive imaging methods do not affect the immune system and have been applied to human subjects before. Translation into clinical applications is therefore feasible. Graphical abstract
Source: Neuroscience - Category: Neuroscience Source Type: research