Exploring the relationship between metal exposure, BDNF, and behavior in adolescent males

CONCLUSION: Exposure to As and Cd was associated with BDNF gene DNA methylation BDNF gene and serum BDNF, respectively. Associations with DNA methylation may be attributable to a higher variability over time in circulating BDNF concentrations than in the methylation status of this gene. Caution should be taken when interpreting the results relating postnatal Pb and Hg to behavioral functioning. Further studies are needed to verify these findings.PMID:34757248 | DOI:10.1016/j.ijheh.2021.113877

Source: International Journal of Hygiene and Environmental health - November 10, 2021 Category: Environmental Health Authors: Andrea Rodr íguez-Carrillo Vicente Mustieles Shereen Cynthia D'Cruz Louis Legoff Fernando Gil Pablo Olmedo Iris Reina-P érez Antonio Mundo Marina Molina Fatima Smagulova Arthur David Carmen Freire Mariana F Fern ández Source Type: research