The influence of CYP2R1 polymorphisms and gene-obesity interaction with hypertension risk in Chinese rural population

Several studies have reported that variants in CYP2R1 have been linked with an increased risk of hypertension. However, the interaction between CYP2R1 variants and environmental factors on the susceptibility of hypertension remained unclear. Therefore, this study evaluated the influence of CYP2R1 polymorphisms on hypertension susceptibility, and explored the interaction effect of CYP2R1 variations and obesity on the disease.

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 10, 2021 Category: Nutrition Authors: Ze Xu, Dongdong Zhang, Jiankui Lin, Xing Li, Yaping Liu, Jiaojiao Gao, Yuan Xue, Yujing Zhang, Runrong Ding, Guoyu Huang, Tong Zhao, Haoyue Huang, Chenxi Gu, Wenjie Li Source Type: research