Influence of Genetic Polymorphisms Involved in the Hypothalamic-Pituitary-Adrenal Axis and their Interactions with Environmental Factors on Antidepressant Response.

CONCLUSIONS: Our results support a definite role for CRHR1 in the pharmacogenetics of antidepressant drugs. This may contribute to interpatient differences in their responses to antidepressant drugs. PMID: 24422887 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24422887?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - January 15, 2014 Category: Neuroscience Authors: Geng LY, Ye DQ, Shi YY, Xu Z, Pu MJ, Li ZY, Li XL, Li Y, Zhang ZJ Tags: CNS Neurosci Ther Source Type: research