What is the normal tissues morbidity following Helical Intensity Modulated Radiation Treatment for cervical cancer?

What is the normal tissues morbidity following Helical Intensity Modulated Radiation Treatment for cervical cancer? Radiother Oncol. 2015 Mar 4; Authors: Mouttet-Audouard R, Lacornerie T, Tresch E, Kramar A, Le Tinier F, Reynaert N, Leblanc E, Narducci F, Lartigau E, Nickers P Abstract BACKGROUND AND PURPOSE: To report on normal tissues morbidity following IMRT for cervix cancer. MATERIAL AND METHODS: The first 61 patients of a prospective series were included. 50Gy to the PTV 1(pelvis) and 60Gy to the PTV 2 (centro-pelvic disease and GTV nodes) were delivered concomitantly in 28 fractions, followed by a brachytherapy boost. For the small bowel, 50Gy was the maximal dose, while V45 and V40 had to be
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research

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CONCLUSION: The lifetime attributable risk of cancer incidence and mortality due to radiation exposure is not trivial. Therefore efforts should be made to reduce patient doses while maintaining image quality. PMID: 32871427 [PubMed - indexed for MEDLINE]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Clin Imaging Source Type: research
CONCLUSION: LncRNA CASC15 has the potential to become a new therapeutic target or marker for a variety of tumors. PMID: 32962611 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
Conditions:   Malignant Neoplasm;   Malignant Neoplasm of Rectum;   Malignant Neoplasm of Anus;   Malignant Neoplasm of Urinary Bladder;   Malignant Neoplasm of Cervix;   Malignant Neoplasm of Ovary;   Malignant Neoplasm of Prostate;   Malignant Neoplasm of Large Intestine;   M alignant Neoplasm of Colon;   Gynecologic Cancer Intervention:   Biological: Capsules containing either dietary fiber or placebo Sponsors:   Sahlgrensk...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractObjectivesTetrandrine, a natural bisbenzylisoquinoline alkaloid, possesses promising anticancer activities on diverse tumours. This review provides systematically organized information on cancers of tetrandrinein vivo andin vitro, discuss the related molecular mechanisms and put forward some new insights for the future investigations.Key findingsAnticancer activities of tetrandrine have been reported comprehensively, including lung cancer, colon cancer, bladder cancer, prostate cancer, ovarian cancer, gastric cancer, breast cancer, pancreatic cancer, cervical cancer and liver cancer. The potential molecular mechani...
Source: Journal of Pharmacy and Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research
In this report, a group of experts of the Spanish Society of Medical Oncology (SEOM), the Spanish Society of Medical Radiology (SERAM), and Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM) provide an up-to-date review and a consensus guide on these issues. PMID: 32623581 [PubMed - as supplied by publisher]
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Tags: Clin Transl Oncol Source Type: research
CONCLUSION: We found that 1-in-11 cancer survivors developed a SPC. Given the increasing number of cancer survivors and the importance of SPC as a cause of cancer death, there is a need for increased screening for and prevention of SPC. PMID: 32356175 [PubMed - indexed for MEDLINE]
Source: Clinical Prostate Cancer - Category: Cancer & Oncology Authors: Tags: J Cancer Res Clin Oncol Source Type: research
Conclusions: Most cancers may be insensitive to social development. Internal factors, including aging, may be a key factor for the occurrence of cancer. PMID: 32462031 [PubMed - in process]
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
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