The expression and clinical significance of ER β/ERα in ovarian cancer: can we predict the effectiveness of platinum plus taxane therapy?

ConclusionA high level of ER β and not ERα expression can predict the efficacy of front-line platinum plus taxane chemotherapy in stage III HGSOC patients. The status of estrogen receptor beta can be considered as one of the possible predictors for evaluating the effectiveness of ovarian cancer therapy.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research