Mechanism of the Effects of Sodium Channel Blockade on the Arrhythmogenic Substrate of Brugada Syndrome

The mechanisms by which sodium channel blockade and high-rate pacing modify electrogram substrates of Brugada syndrome (BrS) have not been elucidated.

Source: Heart Rhythm - November 3, 2021 Category: Cardiology Authors: Koonlawee Nademanee, Gumpanart Veerakul, Akihiko Nogami, Qing Lou, M élèze Hocini, Ruben Coronel, Elijah R. Behr, Arthur Wilde, Bastiaan J. Boukens, Michel Haissaguerre Source Type: research