Identification of Novel, Immunogenic HLA –DR‐Presented Prevotella copri Peptides in Patients With Rheumatoid Arthritis

ConclusionThe majority of the RA patients had Pc immune responses. The correlation of IgA Pc antibody responses, particularly to Pc-p27, with ACPA supports the hypothesis that specific microbial antigens in the mucosa have a role in shaping or amplifying immune responses in RA joints.

Source: Arthritis and Rheumatology - October 22, 2021 Category: Rheumatology Authors: Annalisa Pianta, Geena Chiumento, Kristina Ramsden, Qi Wang, Klemen Strle, Sheila Arvikar, Catherine E. Costello, Allen C. Steere Tags: Brief Report Source Type: research