Crohn’s disease: Foods and drinks to avoid a painful flare-up – including some vegetables

A FLARE-UP of Crohn's disease can lead to urgent bowel movements, diarrhoea and excruciating abdominal pain. If you have to live with this health condition, you would want to avoid aggravating it at all costs.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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CONCLUSIONS: We found low certainty evidence that transcranial direct current stimulation may improve pain intensity compared to sham stimulation. We could not reach any conclusions on the efficacy of any other interventions on pain intensity, pain frequency, and treatment success. The certainty of the evidence was very low due to the low numbers of studies and participants in each comparison and clinical heterogeneity amongst the studies. While no serious or total adverse events were elicited explicitly with any of the treatments studied, the reported events were very low. The certainty of the evidence for all comparisons...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research
JPEN J Parenter Enteral Nutr. 2021 Oct 7. doi: 10.1002/jpen.2273. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Exclusive enteral nutrition (EEN) is not routinely used as induction therapy for adults with active Crohn's Disease (CD). The aim of this study was to assess the effectiveness of EEN with oral polymeric formula as an adjunct for inducing clinical and biochemical remission in adults with active CD.METHODS: We performed a retrospective analysis of data from January 2018 to September 2019 on all patients with active CD who commenced EEN. Primary endpoint was clinical remission (CDAI ≤150) or response (100-po...
Source: JPEN Journal Of Parenteral And Enteral Nutrition - Category: Nutrition Authors: Source Type: research
IRRITABLE bowel syndrome causes abdominal symptoms that include constipation, diarrhoea, or both. However, the condition does not damage a person's bowel like ulcerative colitis or Crohn's disease can. Symptoms can consist of flare ups that can cause excruciating pain and can make going about your daily life uncomfortable. For years, IBS has often been diagnosed before another, more serious condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
New digital health tech targeted to fight autoimmune diseases or their symptoms are diverse and creative. These often completely different illnesses, like type 1 diabetes, inflammatory bowel disease, rheumatoid arthritis, and multiple sclerosis, indicate an immune system dysfunction. Immune cells and mechanisms target the body’s own cells and structures, deconstructing it bit by bit and inducing inflammation. An estimated 24-50 million people in the US alone are living with autoimmune conditions. It affects their day-to-day life, but scientists suggest people living with chronic conditions could also be more susc...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Biotechnology Future of Medicine Portable Medical Diagnostics Telemedicine & Smartphones chatbot diabetes digital health sleep optimization chronic pain chronic illness skin coronavirus autoimmune disease Source Type: blogs
Basel, 10 August 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced topline results from its phase III study programme evaluating the investigational medicine etrolizumab in people with moderately to severely active ulcerative colitis. Mixed results were seen in studies evaluating etrolizumab as an induction therapy, and both studies evaluating etrolizumab as a maintenance therapy failed to meet their primary endpoints, showing no significant difference in the proportion of people achieving remission with subcutaneous etrolizumab versus placebo. In the HIBISCUS I induction study, in people without prior anti-tumour ...
Source: Roche Media News - Category: Pharmaceuticals Source Type: news
In this study, we examined the effects of oxytocin on the Aβ-induced impairment of synaptic plasticity in mice. To investigate the effect of oxytocin on synaptic plasticity, we prepared acute hippocampal slices for extracellular recording and assessed long-term potentiation (LTP) with perfusion of the Aβ active fragment (Aβ25-35) in the absence and presence of oxytocin. We found that oxytocin reversed the impairment of LTP induced by Aβ25-35 perfusion in the mouse hippocampus. These effects were blocked by pretreatment with the selective oxytocin receptor antagonist L-368,899. Furthermore, the tr...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
We report a rare case of acute bowel obstruction due to multiple bilateral deep intestinal endometriosis lesions localised in the ileum, ileocaecal valve and upper rectum, requiring synchronous resection in an emergency setting. A 42-year-old woman was referred to our clinic with a diagnosis of obstructing Crohn's disease based on abdominal computed tomography with oral contrast showing a thickened terminal ileum with stenosis, compression of the caecum and proximally dilated small bowel loops. Simultaneous ileocaecal resection and segmental resection of the upper rectum with handsewn end-to-end anastomosis between the sig...
Source: Annals of the Royal College of Surgeons of England - Category: Surgery Authors: Tags: Ann R Coll Surg Engl Source Type: research
CONCLUSIONS: 5-ASA preparations are superior to placebo for the maintenance of surgically-induced clinical remission in patients with CD (moderate certainty). The number needed to treat to prevent one relapse was 13 patients. The evidence for endoscopic remission is uncertain. The sulphasalazine class of 5-ASA agents failed to demonstrate superiority against placebo, 5-ASAs failed to demonstrate superiority compared to no treatment (very low and low certainty). The efficacy of two different doses of the same 5-ASA and the efficacy of 5-ASA compared to purine antimetabolites (azathioprine or 6-mercaptopurine) in maintaining...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
is a chronic inflammatory bowel disease that can affect any part of the gastrointestinal tract from mouth to anus, although the ileum, colon and perineum are most commonly involved. It is characterized by transmural granulomatous inflammation. Crohn's disease is thought to result from a complex interplay of multiple genetic and environmental factors. Alterations in the microbiota signature with reduced microbiota diversity are observed. Diarrhoea, abdominal pain, fatigue, weight loss and fever are hallmarks of Crohn's disease.
Source: Medicine - Category: Internal Medicine Authors: Tags: Inflammatory bowel disease Source Type: research
In conclusion, our study might provide evidence that GQD treats diarrhea maybe involved in modulating gut microbiota and increasing SCFA levels. Introduction Diarrheal diseases cause approximately 1.7 billion new infections and 0.76 million deaths in children of under 5 years of age annually and are thus the second most common cause of mortality in young children in developing countries (Kotloff et al., 2012, 2013). Outbreaks of such diseases are usually related to infection by common causative agents, mainly rotavirus, Salmonella enterica, and diarrheagenic Escherichia coli (Hodges and Gill, 2010; Kolenda et al., ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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