Acid Hydrolysis of Gluten Enhances the Skin Sensitizing Potential and Drives Diversification of IgE Reactivity to Unmodified Gluten Proteins

ConclusionAcid hydrolysis enhances the skin sensitizing capacity of gluten and drives IgE reactivity to more gluten proteins. This property of acid hydrolyzed gluten may be related to the degree of product deamidation, and could be a strong trigger of wheat allergy in susceptible individuals.
Source: Molecular Nutrition and Food Research - Category: Food Science Authors: Tags: Research Article Source Type: research

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' Thus far, it does not look like there's a great degree of severity to it,'Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases, told CNN's State of the Union.WebMD Health News
Source: Medscape Med Students Headlines - Category: Universities & Medical Training Tags: Infectious Diseases News Source Type: news
Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
Really, there's just no other word for it. You may have seen this tweet from Republican representative Marjorie Taylor Green -- and keep in mind that she got a huge majority of votes in her district. And oh yeah, this already had nearly 4,000 likes when snipped. If I have to explain to you why this is stupider than an 80 pound bag of portland cement, there is no hope for you. Then there is Senator Ron Johnson, who won the majority of votes in the entire state of Wisconsin,who accuses Anthony Fauci of  " overhyping " the AIDS epidemic.Discussing the omicron variant, Johnson accused individuals in the U.S...
Source: Stayin' Alive - Category: American Health Source Type: blogs
[Premium Times] Mr Fauci is the Chief Medical Adviser to the U.S. President Joe Biden as well as the Director, the National Institute of Allergy and Infectious Diseases.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Dipeptidyl peptidase-IV (DPP-IV) inhibitors, also known as gliptins, are a class of oral antidiabetic agents. Postmarketing reports have documented the occurrence of angioedema in patients treated with gliptin...
Source: Clinical and Molecular Allergy - Category: Allergy & Immunology Authors: Tags: Review Source Type: research
Background: Allergen avoidance is critical for those with IgE-mediated food allergy (FA) but can only be successful with accurate product information. While the Food and Drug Administration (FDA) maintains the Center for Food Safety and Nutrition (CFSAN) Adverse Event Reporting System (CAERS) to collect adverse event (AE) reports related to foods, there is significant under-reporting and information regarding product labeling issues is limited.Objective: The purpose of this study was to describe allergic reactions associated with accidental oral exposure to sesame and the role of product labeling.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
Background: Beta-lactam antibiotic allergy labels are highly prevalent, though, rarely indicate an allergic intolerance. These patient-reported allergies lead to broad-spectrum antibiotic use, conferred resistance, increased expense and side effects.Objective: To implement and assess the impact of a history-based clinical guideline that directs antibiotic management and beta-lactam allergy relabeling for patients reporting beta-lactam allergies.Methods: Patients with beta-lactam allergy labels were identified by our trained multi-disciplinary team in diverse clinical settings.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
ConclusionsAfter established diagnosis the standard of care is counseling to avoid peanut contact and prescription of emergency medications (oral antihistamines, oral steroids, inhaled β2-agonists, injectable intramuscular epinephrine) as needed. Instruction on the use of these emergency medications should be provided. A preparation for oral immunotherapy (OIT) for 4 to 17 years old peanut allergic children/ adolescents has been recently approved by the regulatory authorities. O IT for peanut allergy shows high efficacy and an acceptable safety profile, improves quality of life, and health economic aspects. Thus ...
Source: Allergo Journal International - Category: Allergy & Immunology Source Type: research
ConclusionThe most important diagnostic measures in determining the diagnosis of peanut allergy are clinical history and detection of sensitizations, also via component-based diagnostics. However, in case of unclear results, the gold standard —an oral food challenge—should always be used.
Source: Allergo Journal International - Category: Allergy & Immunology Source Type: research
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