Africa: Joint Statement By WHO-Unicef-Rotary On World Polio Day

[WHO-AFRO] Today, as the world commemorates World Polio Day with the theme, "One Day. One Focus: Ending Polio - delivering on our promise of a polio-free world!", and Ethiopia launches a nationwide polio vaccination (nOPV2) campaign, we - the World Health Organization (WHO), UNICEF and ROTARY - reaffirm our commitment to continue delivering on our promise of a polio-free world for current and future generations.
Source: AllAfrica News: Polio - Category: Infectious Diseases Source Type: news

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CONCLUSION: The study indicates good accordance between the VA and official reference data for different vaccination rates, especially for children, and indicates that the VA database is suitable for epidemiological studies on vaccines.PMID:34846300 | DOI:10.5414/CP204098
Source: International Journal of Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Authors: Source Type: research
TWiV reviews why children should be vaccinated against COVID-19, increased risk of infection with SARS-CoV-2 Beta, Gamma, and Delta variant compared to Alpha variant in vaccinated but not recovered individuals, and immune correlates of protection from the mRNA-1273 vaccine efficacy trial. Hosts: Vincent Racaniello, Dickson Despommier, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode COVID-19 vaccines for children (Science) Risk of infection with variants (medRxiv) Immune correlates of mRNA-1273 (Science) Letters ...
Source: This Week in Virology - MP3 Edition - Category: Virology Authors: Source Type: podcasts
ConclusionThe Rapid IgG Screen (RIgGS) test can differentiate between low IgG levels associated with agammaglobulinemia and normal IgG antibody levels. Differentiating CVID and hyper IgM was challenging due to the wide range in IgG levels and influence of high IgM. This test can facilitate the identification of patients with primary antibody deficiencies and support polio surveillance initiatives.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
J Virol Methods. 2021 Nov 23:114376. doi: 10.1016/j.jviromet.2021.114376. Online ahead of print.ABSTRACTThe cost-effectiveness of the Sabin inactivated poliovirus vaccine derived from the Sabin strains (S-IPV) and its reduced biosecurity risks during its manufacture make it the vaccine of choice over the IPVs derived from wild-type polioviruses. However, it is difficult to evaluate whether S-IPVs can achieve wild-type poliovirus containment in China, making its development there less attractive. To facilitate the development and adoption of S-IPVs in China, the aim of this study was to develop an alternative neutralizing a...
Source: Journal of Virological Methods - Category: Virology Authors: Source Type: research
[WHO] The thirtieth meeting of the Emergency Committee under the International Health Regulations (2005) (IHR) on the international spread of poliovirus was convened by the WHO Director-General on 3 November 2021 with committee members and advisers attending via video conference, supported by the WHO Secretariat. The Emergency Committee reviewed the data on wild poliovirus (WPV1) and circulating vaccine derived polioviruses (cVDPV). Technical updates were received about the situation in the following State Parti
Source: AllAfrica News: Polio - Category: Infectious Diseases Source Type: news
CONCLUSIONS: Continued efforts to improve access to vaccination services are required in sub-Saharan Africa. Improving vaccination coverage and reducing inequalities requires enhancing access to quality services that are accessible, affordable, and acceptable to all. Vaccination programs should target critical social determinants of health and address barriers to better maternal health-seeking behaviour.PMID:34794824 | DOI:10.1016/j.vaccine.2021.11.005
Source: Vaccine - Category: Allergy & Immunology Authors: Source Type: research
[Premium Times] "We are going to homes, schools, churches, malls, parks, markets, farms as well as all living areas, where a child can be found."
Source: AllAfrica News: Polio - Category: Infectious Diseases Source Type: news
Virus Res. 2021 Nov 15:198633. doi: 10.1016/j.virusres.2021.198633. Online ahead of print.ABSTRACTAn 8-month-old child diagnosed with severe combined immunodeficiency (SCID) was found to be excreting vaccine-derived poliovirus (VDPVs). Five stool samples from the child and stool samples from 24 contacts were collected during the following 7 months. Complete genome sequence by next generation sequencing (NGS) identified 0.7% to 1.4% nucleotide substitutions in the capsid P1 region of the first and the last isolates compared with Sabin 3 strain. Simplot analysis revealed that all isolates were Sabin 3/Sabin 1 recombinants, s...
Source: Virus Research - Category: Virology Authors: Source Type: research
Expert Opin Drug Saf. 2021 Nov 17. doi: 10.1080/14740338.2022.2007882. Online ahead of print.ABSTRACTINTRODUCTION: The DTaP5-IPV-Hib-HepB vaccine is the most recently approved combination hexavalent vaccine. In Europe, it is licensed since 2016 for primary and booster vaccination in infants and toddlers above the age of 6 weeks to provide active immunisation against diphtheria, tetanus, pertussis, poliomyelitis, invasive diseases caused by Haemophilus influenzae type b and hepatitis B. In the US, DTaP5-IPV-Hib-HepB is approved since 2018 in children 6 weeks through 4 years of age. Its safety profile has been extensively do...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Authors: Source Type: research
[The Conversation Africa] For many of us, the case for childhood vaccination seems self-evident. Every year, this powerful public health intervention protects billions of children from deadly and debilitating infections like polio and measles. Yet worldwide, many parents are reluctant - if not outright refusing - to vaccinate their children. This includes parents who have access to vaccines, are well-educated, and have enjoyed the benefits of having their children grow up in a world free of many vaccine-preventable diseases.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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