Use of ketamine and esketamine for depression: an overview of systematic reviews with meta-analyses

ConclusionKetamine and esketamine showed a significant antidepressant action within a few hours or days after administration; however, the long-term efficacy and safety are lacking. In addition, the methodological quality of the reviews was usually critically low, which may indicate the need for higher quality evidence in relation to the theme.
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research