Autism-Linked Gene SYNGAP1 Molds Synaptic Plasticity, Learning

The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain.
Source: The Scientist - Category: Science Tags: News & Opinion Source Type: news

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Neuropharmacology. 2021 Nov 10:108878. doi: 10.1016/j.neuropharm.2021.108878. Online ahead of print.ABSTRACTNeurobiology of social contagion/empathy aims to collaborate with the development of treatments for human disorders characterized by the absence of this response - autism spectrum disorder, schizophrenia, and antisocial personality disorder. Previous studies using sustained aversive stimuli (e.g., neuropathic pain or stress) to induce social contagion behaviors in rodents have demonstrated that these conditions may increase hypernociception, anxiogenic-like effects, and defensive behaviors in cagemates. To amplify th...
Source: Neuropharmacology - Category: Drugs & Pharmacology Authors: Source Type: research
ley Prior to COVID-19, research into teletherapy models for individuals on the autism spectrum was slowly progressing. Following the onset of COVID-19, teletherapy became a necessity for continuity of services, however, research was still emerging for how to translate best practice autism support to the online environment. The aim of this research was to gain insight into the rapid shift to teletherapy for practitioner and service users and the implications for the broader disability sector. Survey responses were collected from 141 allied health practitioners (speech pathologists, occupational therapists, psychologists...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Condition:   Autism Spectrum Disorder Intervention:   Drug: 50 mg naltrexone Sponsor:   State University of New York - Upstate Medical University Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Meeting of the Working Group on the National Mental Health Strategic Plan, April 2019By Saima Wazed and Nazish ArmanDHAKA, Oct 27 2021 (IPS) Mental health is a state of well-being when both your body and your mind are in balance, and you are able to deal with the difficulties and challenges that come your way and easily find joy, peace, and happiness once the challenge is overcome. For many people though, the challenges often remain for too long – the pain of losing someone you dearly loved, being diagnosed with a chronic disease like cancer or a heart condition, losing your family/home/job or feeling like you failed...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Aid Asia-Pacific Featured Headlines Health Poverty & SDGs TerraViva United Nations Women's Health Source Type: news
Disruptive mood dysregulation disorder (DMDD) is a condition in which children or adolescents experience chronically irritable or angry mood. These feelings typically manifest through frequent and intense temper outbursts that can be verbal (eg, yelling) or physical (eg, hitting). These symptoms carry a personal cost, affecting family life, peer relationships, and school functioning. Yet, evidence-based treatment options can be difficult to access. A recent therapeutic solution —Cognitive Bias Modification (CBM)—lies in targeting neurocognitive mechanisms known to maintain and contribute to irritability. In bri...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Editorial Source Type: research
Int J Dev Neurosci. 2021 Oct 22. doi: 10.1002/jdn.10153. Online ahead of print.ABSTRACTNeurological and neuronal disorders are associated with structural, biochemical, or electrical abnormalities in the nervous system. Many neurological diseases have not yet been discovered. Interventions used for the treatment of these disorders include avoidance measures, lifestyle changes, physiotherapy, neurorehabilitation, pain management, medication, and surgery. In the sodium channelopathies, alterations in the structure, expression, and function of voltage-gated sodium channels (VGSCs) are considered as the causes of neurological a...
Source: International Journal of Developmental Neuroscience - Category: Neuroscience Authors: Source Type: research
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