Evaluation of the new BL-RED ( β-Lactamase Rapid Electrochemical Detection) test in positive blood culture broths

New Microbiol. 2021 Oct 25;44(3). Online ahead of print.ABSTRACTThe rapid detection of extended-spectrum β-lactamase Enterobacterales (ESBL-E) in a positive blood culture is important in order to initiate an appropriate antibiotic therapy and thus decrease mortality. We evaluated the new BL-RED (β-Lactamase Rapid Electrochemical Detection) test in 100 positive blood culture broths to detect (in ten minutes) the presence or absence of ESBL-E. The BL-RED test appears to be an easy, rapid and reliable test to detect the presence of ESBL directly in Gram negative bacilli-positive blood culture broths, with good performances (sensibility = 97.3%, specificity = 90.5 %, predictive positive value = 85.7 % and predictive negative value = 98.3%). This test could be useful for therapeutic decisions and adjustments of sepsis empirical antibiotic therapy, particularly in wards where the ecology is unfavorable, such as in intensive care units.PMID:34694415
Source: New Microbiologica - Category: Microbiology Authors: Source Type: research