Adjunct Collection of Additional Biorepository Data From Patients Enrolled in Diabetic Foot Consortium (DFC) Trials

Condition:   Diabetic Foot Ulcer Intervention:   Sponsors:   University of Michigan;   Indiana University;   University of Miami;   University of California, San Francisco;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Stanford University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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CONCLUSION: The study documents the frequency of clinically significant anaerobic bacteria in various infections, and their associations with aerobes in polymicrobial growth. The present study may aid us in devising better therapeutic strategies against both aerobes and anaerobes in anaerobic infections, which is often empirical. Besides, the data can update clinicians with the changing patterns of anaerobic infections, which remains a neglected concern.PMID:34861364 | DOI:10.1016/j.anaerobe.2021.102482
Source: Anaerobe - Category: Microbiology Authors: Source Type: research
In this study, we aimed to compare patients with DFU treated with EGF and those treated with a split-thickness skin graft.METHODS: Patients who were treated for DFU in the general surgery clinic were included in the study. The patients were evaluated retrospectively according to their demographic characteristics, wound characteristics, duration of treatment, and treatment modalities.RESULTS: There were 26 patients in the EGF group and 21 patients in the graft group. The mean duration of treatment was 7 weeks (4-8 weeks) in the EGF group and 5.3 weeks (4-8 weeks) in the graft group (P
Source: Journal of the American Podiatric Medical Association - Category: Podiatry Authors: Source Type: research
This study aims to investigate the potential of the TCC-EZ to reduce foot plantar pressures.METHODS: Twelve healthy participants (six males, six females) were fitted with a removable cast walker, TCC, TCC-EZ, and TCC-EZ with accompanying brace removed. These off-loading modalities were tested against a control. Pedar-X technology measured peak plantar pressures in each condition. Statistical analysis of four regions of the foot (rearfoot, midfoot, forefoot, and hallux) was conducted with Friedman and Wilcoxon signed rank tests. Significance was set at P
Source: Journal of the American Podiatric Medical Association - Category: Podiatry Authors: Source Type: research
In this study, we aimed to compare patients with DFU treated with EGF and those treated with a split-thickness skin graft.METHODS: Patients who were treated for DFU in the general surgery clinic were included in the study. The patients were evaluated retrospectively according to their demographic characteristics, wound characteristics, duration of treatment, and treatment modalities.RESULTS: There were 26 patients in the EGF group and 21 patients in the graft group. The mean duration of treatment was 7 weeks (4-8 weeks) in the EGF group and 5.3 weeks (4-8 weeks) in the graft group (P
Source: Journal of the American Podiatric Medical Association - Category: Podiatry Authors: Source Type: research
This study aims to investigate the potential of the TCC-EZ to reduce foot plantar pressures.METHODS: Twelve healthy participants (six males, six females) were fitted with a removable cast walker, TCC, TCC-EZ, and TCC-EZ with accompanying brace removed. These off-loading modalities were tested against a control. Pedar-X technology measured peak plantar pressures in each condition. Statistical analysis of four regions of the foot (rearfoot, midfoot, forefoot, and hallux) was conducted with Friedman and Wilcoxon signed rank tests. Significance was set at P
Source: Journal of the American Podiatric Medical Association - Category: Podiatry Authors: Source Type: research
Wound classification systems are useful tools to characterise diabetes-related foot ulcers (DFU) and are utilised for the purpose of clinical assessment, to promote effective communication between health profe...
Source: Journal of Foot and Ankle Research - Category: Podiatry Authors: Tags: Methodology Source Type: research
CONCLUSIONS: Reduced concentrations of selected cytokines and growth factors may indicate abnormal activity of the cells that secrete them and affect the healing process of chronic wounds, hindering and delaying the healing process.PMID:34849122 | PMC:PMC8610058 | DOI:10.5114/ada.2020.96702
Source: Advances in Dermatology and Allergology - Category: Dermatology Authors: Source Type: research
The antibiotic-free formulation shows potential as a targeted treatment for antimicrobial-resistant bacteria in chronic wounds such as diabetic foot ulcers, as well as a potential therapy for SARS-CoV-2.Medscape Medical News
Source: Medscape Dermatology Headlines - Category: Dermatology Tags: Infectious Diseases News Source Type: news
CONCLUSIONS: People with diabetes at risk of foot ulceration expressed a clear need for custom-made indoor footwear, and expected such footwear to increase their adherence. Our indoor footwear design provides adequate pressure relief, with better usability, and can be produced at lower costs compared to regular custom-made footwear.Implications for rehabilitationPeople with diabetes at risk of foot ulceration express a need for special indoor footwear.We developed indoor footwear with similar offloading capacity as regular custom-made footwear.The indoor footwear is lighter in weight, easier to don/doff and lower in costs....
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Source Type: research
We report a case of type 1 diabetic 13-year-old girl who developed yellow atrophic plaque with telangiectasia on the extensor aspect of her upper arm.Case Rep Dermatol 2021;13:547 –552
Source: Case Reports in Dermatology - Category: Dermatology Source Type: research
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