Locked-in Syndrome Due to Meningovascular Syphilis: A Case Report and Literature Review

Intern Med. 2021 Oct 19. doi: 10.2169/internalmedicine.8269-21. Online ahead of print.ABSTRACTWe herein report a 46-year-old man presenting with locked-in syndrome secondary to meningovascular syphilis. Brain magnetic resonance imaging (MRI) demonstrated multiple acute infarctions in the left ventromedial pons, right basis pontis, and left basal ganglia. His locked-in syndrome was hypothesized to have been caused by thrombosis of the small paramedian branches of the basilar artery due to syphilitic arteritis. This is a unique case of bilateral ventromedial pontine infarction caused by meningovascular syphilis that presented as locked-in syndrome. Meningovascular syphilis should be included in the differential diagnosis of uncommon stroke, particularly in young men.PMID:34670896 | DOI:10.2169/internalmedicine.8269-21

Source: Internal Medicine - October 21, 2021 Category: Internal Medicine Authors: Yuki Yokota Masaki Ishihara Satoko Ninomiya Kazutaka Mitsuke Satoshi Kamei Hideto Nakajima Source Type: research