I am so f'ing depressed about choosing IM.

I just feel so sad and disappointed at being an IM intern. I have zero passion over the medicine I am practicing. I wish I went into a specialty that was more procedural to be honest, something like anesthesiology or even frankly Radiology. I already have sunk one year into this and will likely waste another year if I decide to reapply and at that point might as well finish residency...oh well...time go write another long ass note that is meant only for billing...
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: General Residency Issues Source Type: forums

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by Lou Zonca, David Holcman Rhythmic neuronal network activity underlies brain oscillations. To investigate how connected neuronal networks contribute to the emergence of theα-band and to the regulation of Up and Down states, we study a model based on synaptic short-term depression-facilitation with afterhyperpolarization (AHP). We found that theα-band is generated by the network behavior near the attractor of the Up-state. Coupling inhibitory and excitatory networks by reciprocal connections leads to the emergence of a stableα-band during the Up states, as reflected in the spectrogram. To better charact...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
(Int J Obstet Anesth. 2021;45:142–149)
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Anesthesia and Analgesia: Regional Analgesia Source Type: research
Purpose of review The purpose of this article is to review new drugs and devices for nonoperating room anesthesia (NORA). Recent findings Remimazolam is an ultra-short-acting, water-soluble intravenous benzodiazepine with a fast onset and offset that has been approved recently for use in procedural sedation. Phase III trials have established the effectiveness of remimazolam sedation compared with placebo and midazolam in gastrointestinal endoscopy and bronchoscopy. More research is required investigating remimazolam in real-world NORA settings, including comparisons with propofol sedation. Oliceridine is a μ-...
Source: Current Opinion in Anaesthesiology - Category: Anesthesiology Tags: AMBULATORY ANESTHESIA: Edited by Girish P. Joshi Source Type: research
(BJOG. 2021;128:594–602)
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research
An incredible fund of literature related to human factors has evolved in the last several decades, with many of the lessons learned having been extrapolated from the aviation industry and subsequently applied to medicine. We have come to understand that “to err is human,” and a majority of serious human errors in medicine are rooted in ineffective communication.1-3 Medical errors have consequences for many victims, including not just patients and their families, but also the healthcare providers who make them, contributing to poor work performa nce, burnout, depression, and even suicidality.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research
Electroconvulsive therapy is one of the oldest and most effective forms of neurostimulation, where electrical current is used to elicit brief, generalized seizures under general anesthesia. When electrodes are positioned to target fronto-temporal cortex, ECT is arguably the most effective treatment for severe major depression, with response rates and times superior to other available antidepressant therapies. Neuroimaging research has been pivotal in improving the field ’s mechanistic understanding of ECT, with a growing number of MRI studies demonstrating hippocampal plasticity after ECT, in line with evidence of up...
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Review Source Type: research
Chemosphere. 2021 Nov 22:133033. doi: 10.1016/j.chemosphere.2021.133033. Online ahead of print.ABSTRACTKetamine is a non-competitive antagonist of NMDA glutamate receptor. It is used as an anesthetic, analgesic, sedative, and anti-depressive in clinical practice and also an illegal recreational drug. The increasing use has contributed to the measurable levels of ketamine in both wastewaters and hospital effluents, classified as an emergent contaminant. Lately, the potential toxicity of ketamine has raised serious concerns about its iatrogenic or illicit use during pregnancy, neonatal and childhood stages. However, to asses...
Source: Chemosphere - Category: Chemistry Authors: Source Type: research
Conclusions: Patients with POCD experience a much higher incidence of new disability after surgery. Baseline cognitive or functional limitations are also risk factors for new disability. Many patients are not aware of their limitations before surgery. Future study is needed to identify practical ways to routinely screen patients and reduce risk. Patients need to be informed of their risk for new disability after surgery to inform their medical decision making.
Source: Annals of Surgery - Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research
Objective: To examine the rate of new and persistent opioid use after endocrine surgery operations Summary of Background Data: A global epidemic of opioid misuse and abuse has been evolving over the past 2 decades with opioid use among surgical patients being a particularly difficult problem. Minimal data exists regarding opioid misuse after endocrine surgical operations. Methods: A retrospective cohort study using the MarketScan identified adult patients who underwent thyroidectomy, parathyroidectomy, neck dissections for thyroid malignancy, and adrenalectomy from 2008 to 2017. Persistent opioid use was ...
Source: Annals of Surgery - Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research
CONCLUSION: Intraoperative low dose ketamine infusion did not improve the overall quality of recovery on POD 1 in patients undergoing breast cancer surgery.PMID:34807494 | DOI:10.1111/ijcp.15010
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
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