The value of studying rare genetic variants and other emerging themes in neurogenetics

Although white matter hyperintensities on fluid-attenuated inversion recovery (FLAIR) brain MRI are frequent incidental findings without any apparent clinical abnormality, they are widely viewed as an imaging marker of cerebral small vessel disease1 and indicate future risk of stroke and other adverse outcomes.2 Furthermore, understanding the origin and risk factors for this common entity is crucial because of its contribution to cognitive impairment and dementia.3 Reducing its occurrence will likely help decrease the dementia burden in the community and lower healthcare expenditures.
Source: Brain - Category: Neurology Source Type: research