Inactivation of AMPK leads to attenuation of antigen presentation and immune evasion in lung adenocarcinoma

Conclusions:The results provide evidence that the immune evasion noted in LKB1 inactivated lung cancer is due to subsequent inactivation of AMPK and attenuation of antigen presentation.PMID:34667030 | DOI:10.1158/1078-0432.CCR-21-2049

Source: Clinical Cancer Research - October 20, 2021 Category: Cancer & Oncology Authors: Yajing Gao Pekka J P P äivinen Sushil Tripathi Eva Domenech-Moreno Iris Poh Ling P L Wong Kari Vaahtomeri Ashwini S Nagaraj Sarang S Talwelkar Marc Foretz Emmy W Verschuren Benoit Viollet Yan Yan Tomi P Makela Source Type: research