Cancers, Vol. 13, Pages 5316: Radiological Patterns of Uveal Melanoma Liver Metastases in Correlation to Genetic Status

In conclusion, our study shows that there is an inverse correlation of the number of metastasis with the DFS and metastasized survival, indicating separate growth patterns. We also revealed that the number and type of metastases is irrelevant to the prognostic mutation status of the tumor, showing that both BAP1- and SF3B1-mutated UM can result in solitary and miliary metastases, indicating that other processes lay ground to the different metastatic patterns.

Source: Cancers - October 22, 2021 Category: Cancer & Oncology Authors: Serdar Yavuzyigitoglu Michael C. Y. Tang Miguel Jansen Kaspar W. Geul Roy S. Dwarkasing Jolanda Vaarwater Wojtek Drabarek Robert M. Verdijk Dion Paridaens Nicole C. Naus Erwin Brosens Annelies de Klein Emine Kilic Tags: Article Source Type: research