Exosomes and Microvesicles from Adipose-derived Mesenchymal Stem Cells Protects the Endothelial Glycocalyx From Lipopolysaccharide Injury
Endothelial glycocalyx (EGX) damage occurs in various pathological states and results in endotheliopathy. Exosomes (ES) and Microvesicles (MS) isolated from adipose-derived mesenchymal stem cells (ASCs) have therapeutic potential. We hypothesized that ASC-derived ES and MS would not affect EGX shedding after injury.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Sharven Taghavi, Sarah Abdullah, Farhana Shaheen, Juan C. Duchesne, Stephen Braun, Chad Steele, Derek Pociask, Jay Kolls, Olan Jackson-Weaver Tags: Trauma, Burn, and Critical Care Source Type: research