Paracetamol in Addition to WHO Step III Opioids in Chronic Cancer Pain Control

Condition:   Pain Interventions:   Drug: Placebo;   Drug: Paracetamol Sponsors:   University Hospital Inselspital, Berne;   Swiss National Science Foundation Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Conclusions: Moraxella keratitis is a less frequent form of bacterial keratitis that appears more prevalent in patients with previous ocular conditions. Early diagnosis of this infection and medical treatment with a conventional corneal ulcer regimen can result in good clinical outcomes without the need for a surgical intervention.
Source: Eye and Contact Lens: Science and Clinical Practice - Category: Opthalmology Tags: Article Source Type: research
Conclusions: Sarcopenia is an important factor to take into account in MPE patients, which could affect the prognosis. Patients who presented sarcopenia during hospitalization showed a worse recovery, with more symptoms including dyspnea, cough, fatigue and pain.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Pleural and mediastinal malignancies Source Type: research
Chronic respiratory diseases are the third leading cause of death, behind cardiovascular diseases and cancer, affecting approximately 550 million of people all over the world. Most of the chronic respiratory diseases are attributable to asthma and chronic obstructive pulmonary disease (COPD) with this latter being the major cause of deaths. Despite differences in etiology and symptoms, a common feature of asthma and COPD is an underlying degree of airways inflammation. The nature and severity of this inflammation might differ between and within different respiratory conditions and pharmacological anti-inflammatory treatmen...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
We report a case of hepatic lymphoepithelioma-like carcinoma-hepatocellular carcinoma subtype (LEL-HCC) in a 41-year-old man with chronic hepatitis C virus (HCV) infection. The patient presented with abdominal pain and further assessment revealed a hypoechoic mass on ultrasonography. Serum alpha-fetoprotein (AFP) was 13 ·6 ng/dl. The patient was diagnosed as hepatocellular carcinoma based on the established triphasic computed tomography (TCT) diagnostic criteria and he underwent a surgical resection of the mass. Microscopic examination showed sheets and cords of malignant epithelial cells intermixed with heavy ...
Source: Journal of Gastrointestinal Cancer - Category: Cancer & Oncology Source Type: research
The negative health consequences of acute ultraviolet (UV) exposure are evident, with reports of 30,000 emergency room visits annually to treat the effects of sunburn in the United States alone. The acute effects of sunburn include erythema, edema, severe pain, and chronic overexposure to UV radiation, leading to skin cancer. Whereas the pain associated with the acute effects of sunburn may be relieved by current interventions, existing post-sunburn treatments are not capable of reversing the cumulative and long-term pathological effects of UV exposure, an unmet clinical need.
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Understanding diseases Source Type: research
CONCLUSIONS: This analysis offers evidence that medicinal cannabis is being framed as a valid medicine advocated by the community, with potential for addressing a range of conditions despite the lack of evidence, and a medicine that is not free of risk.PMID:34802449 | DOI:10.1186/s42238-021-00105-w
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research
CONCLUSION: Intraoperative low dose ketamine infusion did not improve the overall quality of recovery on POD 1 in patients undergoing breast cancer surgery.PMID:34807494 | DOI:10.1111/ijcp.15010
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: This analysis offers evidence that medicinal cannabis is being framed as a valid medicine advocated by the community, with potential for addressing a range of conditions despite the lack of evidence, and a medicine that is not free of risk.PMID:34802449 | DOI:10.1186/s42238-021-00105-w
Source: Australian Family Physician - Category: Primary Care Authors: Source Type: research
Behav Res Ther. 2021 Nov 12;148:103995. doi: 10.1016/j.brat.2021.103995. Online ahead of print.ABSTRACTChronic health conditions (CHCs) are common and associated with functional limitations. Acceptance and commitment therapy (ACT) shows promise in improving functioning, quality of life, and distress across several CHCs. The purpose of this study was to conduct a systematic review of technology-supported ACT for CHCs and perform a meta-analysis on functioning and ACT process outcomes. Multiple databases were systematically searched for randomized controlled trials. A total of 20 unique studies with 2,430 randomized particip...
Source: Behaviour Research and Therapy - Category: Psychiatry & Psychology Authors: Source Type: research
SPRING HOUSE, PENNSYLVANIA, November 17, 2021 – The Janssen Pharmaceutical Companies of Johnson &Johnson today announced topline results from the Phase 2 GALAXI 1 clinical trial which showed rates of clinical remission (Crohn’s Disease Activity Index [CDAI]
Source: Johnson and Johnson - Category: Pharmaceuticals Source Type: news
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