Genetic obesity in children: overview of possible diagnoses with a focus on SH2B1 deletion
Conclusion: Chromosomal microdeletions in 16 p11.2, including the SH2B1 gene, in children are associated with severe, early-onset obesity and comorbidities associated with insulin resistance. Early genetic testing in suspicious patients and early screening for comorbidities is recommended.
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research
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