Human Stem Cell-Derived Thymic Epithelial Cells Enhance Human T Cell Development in a Xenogeneic Thymus.
Capsule SummaryHuman thymic epithelial cell progenitors generated from human pluripotent stem cells with a new protocol can support human thymopoiesis both in reaggregate grafts and in porcine thymic grafts, advancing potential treatment of human thymic insufficiencies.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Rafael Gras-Pena, Nichole M. Danzl, Mohsen Khosravi-Maharlooei, Sean R. Campbell, Amanda E. Ruiz, Christopher A. Parks, William Meng Suen Savage, Markus A. Holzl, Debanjana Chatterjee, Megan Sykes Source Type: research