Effect of chirality on the anticancer activity of Pt(II) and Pt(IV) complexes containing 1R,2R and 1S,2S enantiomers of the trans-1,2-diamino-4-cyclohexene ligand (DACHEX), an analogue of diaminocyclohexane used in oxaliplatin

Dalton Trans., 2021, Advance Article DOI: 10.1039/D1DT02255E, PaperParide Papadia, Alessandra Barbanente, Nicoletta Ditaranto, James D. Hoeschele, Giovanni Natile, Cristina Marzano, Valentina Gandin, Nicola Margiotta Two Pt(II) and four Pt(IV) enantiomerically pure, oxaliplatin-like, compounds containing an unsaturated cyclic diamine as a substitute for thetrans-1,2-diaminocyclohexane used in oxaliplatin, were investigated. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Dalton Trans. latest articles - October 22, 2021 Category: Chemistry Authors: Paride Papadia Source Type: research