Differences in prostate cancer genomes by self-reported race: Contributions of genetic ancestry, modifiable cancer risk factors, and clinical factors

CONCLUSIONS: Tumor genomics differed by race even after accounting for clinical characteristics. Equalizing access to care may not fully eliminate such differences. Therapies for alterations more common in racial minorities are needed. Tumor genomic differences should not be assumed to be entirely due to germline genetics.PMID:34667026 | DOI:10.1158/1078-0432.CCR-21-2577

Source: Clinical Cancer Research - October 20, 2021 Category: Cancer & Oncology Authors: Konrad H Stopsack Subhiksha Nandakumar Kanika Arora Bastien Nguyen Samantha E Vasselman Barbara Nweji Sean M McBride Michael J Morris Dana E Rathkopf Susan F Slovin Daniel C Danila Karen A Autio Howard I Scher Lorelei A Mucci David B Solit Mithat Gonen Yu Source Type: research