Prolonged impairment of short-chain fatty acid and L-isoleucine biosynthesis in gut microbiome in patients with COVID-19

SARS-CoV-2 infection is associated with altered gut microbiota composition. Phylogenetic groups of gut bacteria involved in the metabolism of short chain fatty acids were depleted in SARS-CoV-2-infected patients. We aimed to characterize functional profile of gut microbiome in patients with COVID-19 before and after disease resolution.

Source: Gastroenterology - October 20, 2021 Category: Gastroenterology Authors: Fen Zhang, Yating Wan, Tao Zuo, Yun Kit Yeoh, Qin Liu, Lin Zhang, Hui Zhan, Wenqi Lu, Wenye Xu, Grace C.Y. Lui, Amy Y.L. Li, Chun Pan Cheung, Chun Kwok Wong, Paul K.S. Chan, Francis K.L. Chan, Siew C. Ng Source Type: research