Gene sequencing in ovarian cancer: continually moving targets

BJOG. 2021 Oct 19. doi: 10.1111/1471-0528.16978. Online ahead of print.ABSTRACTRoutine BRCA1/2 sequencing in ovarian cancer patients has come a long way since referrals to clinical genetics for sequencing were based upon the often imperfect assessment of family history in a gynaecological surgery or medical oncology clinic and the subsequent determination that the risk of an underlying genetic abnormality was above a particular threshold (often 10%).PMID:34665910 | DOI:10.1111/1471-0528.16978
Source: BJOG : An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Source Type: research