RapiGEN BIOCREDIT Malaria Ag RDTs WHO Prequalification Study

Conditions:   Malaria;   Diagnoses Disease;   RDT Intervention:   Diagnostic Test: Rapid diagnostic test Sponsors:   Foundation for Innovative New Diagnostics, Switzerland;   University of Khartoum;   Eijkman Institute for Molecular Biology Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Mini Rev Med Chem. 2021 Nov 24. doi: 10.2174/1389557521666211124143117. Online ahead of print.ABSTRACTAmong all the parasitic diseases in humans, malaria is the most significant and malicious one. The widespread species are Plasmodium falciparum and Plasmodium vivax, but the infection caused by former is the deadliest. According to November 2018 report of the World Health Organization (WHO), a total of 219 million cases of malaria reported globally in 2017 which led to an estimated 435,000 deaths. Mortality due to malaria is estimated at 1.5 - 2.7 million deaths each year. Among all the complications associated with Plasmo...
Source: Mini Reviews in Medicinal Chemistry - Category: Chemistry Authors: Source Type: research
We report a case of scrub typhus-associated nephrotic syndrome with acute kidney injury in a five-year-old female with uneventful outcome.PMID:34818870 | DOI:10.4103/0972-9062.321744
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Authors: Source Type: research
CONCLUSION: Study revealed that in Kangra district, An. fluviatilis sibling-species U is predominant followed by species T, and both are non-vectors. The absence of malaria parasite and zoophagic nature of An. fluviatilis established through blood meal analysis, confirmed that both U and T are non-vector sibling-species.PMID:34818868 | DOI:10.4103/0972-9062.321745
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Authors: Source Type: research
CONCLUSION: This is a unique study on diversity of microbiota of An. stephensi from breeding water, developmental stages and adults. Different culture media used enhanced the isolation of diverse bacteria. The presence of Micrococcus and Leucobacter in different life stages indicates their adaptation in An. stephensi as symbionts which need further evaluation for their role in paratransgenesis.PMID:34818867 | DOI:10.4103/0972-9062.289392
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Authors: Source Type: research
CONCLUSION: The present study showed that despite having congenial environmental conditions, Jammu division faces a great threat of VBDs and the increase in the number of cases in future cannot be ruled out. Japanese encephalitis registered its presence for the first time in the division.PMID:34818860 | DOI:10.4103/0972-9062.321746
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Authors: Source Type: research
J Vector Borne Dis. 2021 Jan-Mar;58(1):1-11. doi: 10.4103/0972-9062.318313.ABSTRACTIncreased outbreaks of mosquito borne diseases like the deadly parasitic disease, malaria and arboviruses like Zika, yellow fever and dengue viruses around the world have led to increased interest in traps that could effectively be used against mosquitoes. For example, a Google search at the time of this writing, asking, 'which is the best way of trapping mosquitoes?' produced 35.5 million search results. Regardless of the interest in the subject, scientists have yet to find a definitive answer to these questions. One area that has been expl...
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Authors: Source Type: research
ConclusionThe sensitivity of the indirect ELISA method with the recombinant PvCSP-VK210 antigen was 61.42%, which is the first report from Iran.
Source: European Journal of Medical Research - Category: Research Source Type: research
Conclusion: Since all of these patients presented to our clinic as presumptive COVID patients, our series highlights the need of careful evaluation of patients with happy hypoxia for causes other than COVID-19.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical problems Source Type: research
AbstractPatients with cerebral malaria with polymorphicCytochrome P450 2C19 (CYP2C19) genotypes who receive concurrent treatment with quinine are at risk of inadequate or toxic therapeutic drug concentrations due to metabolic drug interactions. The study aimed to predict the potential dose regimens of quinine when coadministered with phenobarbital in adult patients with cerebral malaria and complications (e.g., lactic acidosis and acute renal failure) and concurrent with seizures and acute renal failure who carry wild-type and polymorphicCYP2C19. The whole-body physiologically based pharmacokinetic (PBPK) models for quinin...
Source: CPT: Pharmacometrics and Systems Pharmacology - Category: Drugs & Pharmacology Authors: Tags: ARTICLE Source Type: research
Though most of Panam á is free from malaria, localized foci of transmission persist, including in the Guna Yala region. Government-led entomological surveillance using an entomological surveillance planning too...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
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