The effects of quercetin on seizure, inflammation parameters and oxidative stress in acute on chronic tramadol intoxication

CONCLUSION: chronic administration of quercetin showed decreased oxidative/nitrosative stress in the liver, kidney, adrenal, and heart tissues. Quercetin plus naloxone decreased oxidative stress in the heart and adrenal tissues, but adverse effects on the brain cortex and hepatic function. Single-dose quercetin reduced cardiac oxidative stress.PMID:34666816 | DOI:10.1186/s40360-021-00532-8
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Authors: Source Type: research