Giant cell arteritis with cervical radiculopathy mimicking polymyalgia rheumatica and elderly-onset rheumatoid arthritis: a case report

ConclusionsIf the patient was misdiagnosed with polymyalgia rheumatica or elderly-onset rheumatoid arthritis based on only clinical symptoms and laboratory data, his symptoms might not improve due to insufficient steroid dose and vascular complications may occur later. Although rare, peripheral neuropathy in giant cell arteritis may include cervical radiculopathy. The musculoskeletal ultrasound and precise neurological examination were the turning points for the diagnosis of this case, and making a careful diagnosis using these methods was important.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research

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We present a rare case of anterior interosseous nerve neuropathy affecting only the flexor digitorum profundus to the index finger and occurring after shoulder arthroscopy. This unique presentation used a combination of both electrodiagnostic testing and neuromuscular ultrasound to obtain an accurate diagnosis and highlights the importance of these complementary tests in the evaluation of nerve disorders. To our knowledge, anterior interosseous nerve neuropathy after shoulder arthroscopy affecting only the flexor digitorum profundus to the index finger has not been previously described in the literature.
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Case Reports Source Type: research
ConclusionsThe sonographic findings corresponded to chest X-ray and computed tomography imaging in this patient and to previously reported sonographic characteristics of mycotic abscesses in other organs. Lung ultrasound may be a tool to identify pulmonary aspergilloma, especially as a point-of-care imaging tool and where other imaging modalities are inaccessible.
Source: Infection - Category: Infectious Diseases Source Type: research
Conclusions: HEART-CT reclassified a large proportion of patients as safe for discharge, maintained a high sensitivity for detecting 30-day MACE, and had an acceptable ED LOS. Future studies should test the extent to which more automated clinical decision support improves provider adoption and clinical outcomes of HEART-CT.
Source: Critical Pathways in Cardiology - Category: Cardiology Tags: Original Study Source Type: research
AbstractOur previous studies have identified miR-483-3p to be highly expressed in synoviocytes from patients with rheumatoid arhtirits (RA); however, its effects on inflammation of RA fibroblast-like synoviocytes (FLSs) have remained unclear. The expression of miR-483-3p and cytokines in RA FLSs was detected using quantitative real-time polymerase chain reaction. Enzyme-linked immunosorbent was conducted to determine interleukin (IL)-33 production from RA FLSs. Western blotting was employed to quantify the levels of p-ERK and total ERK. Overexpressed miR-483-3p significantly increased the mRNA and protein expression of IL-...
Source: Inflammation - Category: Allergy & Immunology Source Type: research
This study aimed to demonstrate the effects of (Ac)5GP on migration, invasion, and inflammation of TNF- α-stimulated rheumatoid arthritis (RA) FLS (MH7A cell) and to explore the involved mechanisms. MTT assay was used to determine the applied non-cytotoxic doses of (Ac)5GP (12.5, 25, 50 μM)in vitro. Results of wound-healing, transwell, and phalloidin staining assays indicated that (Ac)5GP reduced the migration, invasion, and F-actin cytoskeletal reorganization of TNF- α-stimulated MH7A. Results of ELISA and western blot assays confirmed that (Ac)5GP reduced TNF- α-induced production of pro-inflammatory...
Source: Inflammation - Category: Allergy & Immunology Source Type: research
Chem. Commun., 2021, Advance Article DOI: 10.1039/D1CC05658A, CommunicationJun-An Xiao, Hai Peng, Jin-Shao Liang, Ru-Fang Meng, Wei Su, Qi Xiao, Hua Yang A series of benzo[b]carbazole and cyclohepta[b]indole derivatives were afforded in a 77% average yield with excellent regioselectivities enabled by Au(I)/Sc(III) bimetallic relay catalysis. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
ConclusionBy constructing a multi-path 3D CNN to fully extract candidate target features, it accurately identifies pulmonary nodules with different sizes, shapes, and background information. In addition, the proposed general framework is also suitable for similar 3D medical image classification tasks.
Source: International Journal of Computer Assisted Radiology and Surgery - Category: Intensive Care Source Type: research
ConclusionWe formulated a method of predicting the logarithm posterior probability using two FDG models. We validated that the method can detect abnormal findings in CXRs and BCTs with both an acceptable performance for testing and a comparatively light workload for training.
Source: International Journal of Computer Assisted Radiology and Surgery - Category: Intensive Care Source Type: research
Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
Conclusions: Completeness of sacral fractures had weak interobserver reliability among fellowship-trained orthopaedic trauma surgeons. Sacral fractures that were considered incomplete by all surgeons did have occult instability. These results highlight the large potential for error created by using sacral fracture completeness as a criterion to rule out occult instability. Level of Evidence: Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Source: Journal of Orthopaedic Trauma - Category: Orthopaedics Tags: Original Article Source Type: research
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