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Pulmonary Hypertension
Source: Cardiology Clinics - Category: Cardiology Source Type: research

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Conclusion The study showed that copeptin and hs-CRP levels were increased in patients with VOC, and a significant relationship was fo und between RV dysfunction in VOC patients. As a conclusion copeptin can be used as a potential biomarker in predicting VOC crisis in SCA patients and in early detection of patients with SCA who have the potential to develop RV dysfunction.
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research
Annals of the American Thoracic Society,Volume 18, Issue 12, Page 2095-2098, December 2021.
Source: Annals of the American Thoracic Society - Category: Respiratory Medicine Authors: Source Type: research
BEERSE, BELGIUM, 30 November 2021 – The Janssen Pharmaceutical Companies of Johnson &Johnson today announced the submission of a Type II variation application to the European Medicines Agency (EMA) seeking approval of a new treatment option for IMBRUVICA® (ibrutinib) as a fixed-duration combination with venetoclax (I+V) for adult patients with previously untreated chronic lymphocytic leukaemia (CLL)."Ibrutinib was the first approved Bruton’s tyrosine kinase inhibitor and over the past seven years has become a key treatment for CLL and some other B-cell malignancies, treating more than 250,000 patie...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Hum Immunol. 2021 Nov 26:S0198-8859(21)00259-7. doi: 10.1016/j.humimm.2021.11.006. Online ahead of print.ABSTRACTPulmonary hypertension (PH) is a life-threatening pathological state with elevated pulmonary arterial pressure, resulting in right ventricular failure and heart functional failure. Analyses of human samples and rodent models of pH support the infiltration of various immune cells, including neutrophils, mast cells, dendritic cells, B-cells, T-cells, and natural killer cells, to the lungs and pulmonary perivascular regions and their involvement in the PH development. There is evidence that macrophages are presente...
Source: Human Immunology - Category: Allergy & Immunology Authors: Source Type: research
Asian J Surg. 2021 Nov 26:S1015-9584(21)00724-7. doi: 10.1016/j.asjsur.2021.11.025. Online ahead of print.NO ABSTRACTPMID:34844829 | DOI:10.1016/j.asjsur.2021.11.025
Source: Asian Journal of Surgery - Category: Surgery Authors: Source Type: research
Interstitial lung diseases (ILDs) are diverse parenchymal pulmonary disorders, primarily characterised by alveolar and interstitial inflammation and/or fibrosis, and sharing pathophysiological similarities. Thus, patients generally harbour common respiratory symptoms, lung function abnormalities and modified exercise adaptation. The most usual and disabling complaint is exertional dyspnoea, frequently responsible for premature exercise interruption. Cardiopulmonary exercise testing (CPET) is increasingly used for the clinical assessment of patients with ILD. This is because exercise performance or dyspnoea on exertion cann...
Source: European Respiratory Review - Category: Respiratory Medicine Authors: Tags: Interstitial and orphan lung disease, Pulmonary pharmacology and therapeutics Ventilatory efficiency and its clinical prognostic value in cardiorespiratory disorders Source Type: research
Non-coding RNAs (ncRNAs) are involved in various cellular processes. There are several ncRNA classes, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs). The detailed roles of these molecules in pulmonary hypertension (PH) remain unclear. We systematically collected and reviewed reports describing the functions of ncRNAs (miRNAs, lncRNAs, and circRNAs) in PH through database retrieval and manual literature reading. The characteristics of identified articles, especially the experimental methods, were carefully reviewed. Furthermore, regulatory networks were constructed using ncRNAs an...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Conditions:   Bronchopulmonary Dysplasia;   Pulmonary Hypertension;   Premature Birth Interventions:   Diagnostic Test: Echocardiography;   Diagnostic Test: NT-proBNP Sponsors:   Universitair Ziekenhuis Brussel;   AZ Sint-Jan AV;   Universitaire Ziekenhuizen Leuven;   GZA Ziekenhuizen Campus Sint-Augustinus;   Ziekenhuis Netwerk Antwerpen (ZNA);   Ziekenhuis Oost-Limburg;   University Hospital, Ghent Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: Pulmonary arterial hydatidosis may mimic chronic thromboembolic pulmonary hypertension and these patients can be diagnosed with pulmonary endarterectomy. Surgery may be a therapeutic option for patients who do not respond to medical therapy if the cystic lesions are surgically accessible. Pulmonary endarterectomy should be performed only in expert centers because of the high risk of perioperative morbidity, mortality, and postoperative recurrence.PMID:34843694 | DOI:10.1016/j.athoracsur.2021.10.035
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
Hellenic J Cardiol. 2021 Nov 26:S1109-9666(21)00183-4. doi: 10.1016/j.hjc.2021.10.002. Online ahead of print.NO ABSTRACTPMID:34843997 | DOI:10.1016/j.hjc.2021.10.002
Source: Hellenic Journal of Cardiology - Category: Cardiology Authors: Source Type: research
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