Case Report: Covid-19 in Multiple Sclerosis Patients Treated With Ocrelizumab: A Case Series

Conclusion: This case series highlights the large variability of the course of COVID-19 in ocrelizumab-treated MS patients. The challenges encountered by the healthcare system in the early phase of the COVID-19 pandemic might have contributed to the case fatality ratio observed in this series. Higher MS-related disability was associated with a more severe COVID-19 course.
Source: Frontiers in Neurology - Category: Neurology Source Type: research

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Conclusions: Our results highlight the necessity of scientific and patient organizations in taking joint action to increase awareness on health-related issues during the pandemic and to provide accurate and up-to-date guidance for PwMS. Online information and communications technology (ICT) tools for polling public belief and behavior may prove valuable as means of retaining active routes of communication between stakeholders.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion Our data support EID of ocrelizumab as potential risk mitigation strategy in times of the COVID-19 pandemic. Classification of Evidence This study provides Class IV evidence that for patients with RRMS, an EID of at least 4 weeks does not diminish effectiveness of ocrelizumab.
Source: Neurology Neuroimmunology and Neuroinflammation - Category: Neurology Authors: Tags: MRI, Clinical trials Observational study (Cohort, Case control), COVID-19, Multiple sclerosis Article Source Type: research
J Cell Immunol. 2021;3(2):68-77. doi: 10.33696/immunology.3.080.ABSTRACTThe ongoing pandemic of the novel coronavirus of 2019 (COVID-19) has resulted in over 1 million deaths, primarily affecting older patients with chronic ailments. Multiple sclerosis (MS) patients have been deemed particularly vulnerable given their high rates of disability and increased susceptibility to infections. There have also been concerns regarding disease-modifying therapy (DMT) during the pandemic as many DMTs may increase the risk of infection due to some of their immunosuppressive properties. Furthermore, due to MS-related chronic inflammator...
Source: Cellular Immunology - Category: Allergy & Immunology Authors: Source Type: research
With nearly 200,000 Americans dead from COVID-19 and millions more who lost their health insurance when they lost their jobs this year, President Donald Trump tried this week—as he has done throughout his presidency—to change the conversation. On Sunday, the President issued a new executive order aimed at lowering prescription drug prices, an issue dear to many voters, and boasted on Twitter that “prices are coming down FAST.” The reality is more complicated. Trump’s new executive order, which revokes and replaces a different executive order on drug prices that he signed in July, directs the...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized 2020 Election COVID-19 Explainer News Source Type: news
DiscussionThe use of common tools for neurological examination could improve tele-neurology practice for both general neurologists and MS specialists, and quality of care for people with MS.
Source: Neurological Sciences - Category: Neurology Source Type: research
Jeiri Flores is normally a busy, upbeat 29-year-old. But amid the COVID-19 pandemic, her go-to thought has been dark. “If I get this,” she thinks, “I’m gonna die.” This is not an unfounded fear. Flores has cerebral palsy, uses a wheelchair and needs assistance with everyday tasks, including making food and getting dressed. Her disability means it’s tougher for her immune system to kick illnesses; she’s still recovering from a bout of pneumonia she had in January. So beating COVID-19 could easily mean a protracted battle and months in a hospital—a prospect that comes with a c...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
  Day 1,364 of the COVID-19 quarantine (well, at least it feels like it). How are you holding up? If you’re like most people, you’re not having much fun. But if you already struggle with anxiety, depression or another mental health issue, these days of isolation and uncertainty can feel like absolute torture. In today’s Not Crazy episode, Gabe laments the loss of his routine — those regular activities he clung to religiously to keep his mental health in check.  Now what is he supposed to do? Tune in for a special quarantine episode. Together, we will grieve our old routines and discuss...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic General Health-related Mental Health and Wellness Not Crazy Podcast Self-Help Source Type: blogs
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